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Description
3F, Supplementary Table 4)

2.3 Diagnosis and management Peripheral fatigue can be quantified through objective assessments of strength and aerobic capacity, while central fatigue is evaluated using self-reports and validated questionnaires that capture the patients perception of physical and mental exertion impacts on their activities and exertion levels

Recent studies have used RNA aptamers to reveal nuclear changes in TDP-43 in spinal and cortical neurons of ALS patients prior to traditional cytoplasmic pathology in vulnerable cells [19]

PMID: 71 PellissierL.Pinto-FigueroaE.Niculita-HirzelH.MooraM.VillardL.GoudetJ.et al
The urogenital sinus also forms the bulbourethral glands, and the prostatic and membranous portion of the urethra

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