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The phosphorylated and activated RB binds to transcriptor factors such as E2F families, leading to transcription of various genes involved in different cellular responses and particularly in the activation of cell cycle progression beyond the G1/S transition

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Eisenberg MA, Deboever N, Hofstetter WL, Mehran RJ, Rice DC, Rajaram R, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Antonoff MB

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