glutathione pathways in the brain Genetic defect synthesis and neurodegenerative diseases Comment "Yes" to know the

Mechanisms of cognitive impairment in cerebral small vessel disease: multimodal MRI results from the St Georges cognition and neuroimaging in stroke (SCANS) study

Gut triglyceride production

Early pathogenic events are characterized by synaptic dysfunction and mitochondrial impairment, which are strongly linked to increased reactive oxygen species (ROS) levels, disrupted intracellular Ca 2+ homeostasis, and decreased adenosine triphosphate (ATP) production 83

[DOI] [PubMed] [Google Scholar] 265.Ibrahim S.F., Osman K., Das S., Othman A.M., Majid N.A., Rahman M.P.A

In contrast, pathways involved in metabolism, such as alanine, aspartate, and glutamate metabolism, biosynthesis of secondary metabolites, and C5-branched dibasic acid metabolism, displayed a balance of upregulated and downregulated genes

The results revealed that the DEPs were significantly enriched in the following pathways: cytokine-cytokine receptor interaction, chemokine signaling pathway, IL-17 signaling pathway, TNF signaling pathway, and JAK-STAT signaling pathway