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Thus, targeting glutamine metabolism not only inhibits glutamine-dependent pathways, but also leads to a marked decrease in p-STAT1 and p-STAT3dependent IDO expression resulting in a robust reversal of the kynurenine/tryptophan ratio

W.St JohnP

[DOI] [PMC free article] [PubMed] [Google Scholar] Bashar, A

Cellular senescence in cancer: molecular mechanisms and therapeutic targets

Shchedrina VA, Zhang Y, Labunskyy VM, Hatfield DL, Gladyshev VN

Ascorbic acid is classified as an antioxidant due to the low electron potential and resonance stability of ascorbate and the ascorbyl radical
