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In general, system Xc facilitates the extracellular transport of high intracellular concentrations of glutamate, whereas the anionic form of cysteine is transported in exchange for glutamate (76)

De tino B, Strange BA, Dolan RJ

FIQR is a holistic indicator of FM impact in terms of pain, function, and other common symptoms of FM

Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis

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Specifically, SIRT7 is a target of miR-20b, and the inhibition of miR-20b increases the mRNA and protein expression of SIRT7 by direct targeting of the 3-UTR of SIRT7 in HG-treated podocytes, alleviating HG-induced podocyte apoptosis (Qi et al., 2022a)
