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This study was conducted according to the guidelines laid down in the Declaration of Helsinki, and all procedures involving research study participants were approved by the ethics committee of the Tehran University of Medical Sciences (Ethic code: IR.TUMS.EMRI.REC.1401.075)

Regulation of mediator release by human basophils: importance of the sequence and time of addition in the combined action of different agonists

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In the Phase 3 REDEFINE 1 trial, cagrilintide monotherapy achieved 11.8% average weight loss over 68 weekscomparable to semaglutide but with a notably lower incidence of nausea and vomiting, making it a potential option for patients who dont tolerate GLP-1 medications well