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R81A, R81Q, and T313A n = 7

These effects were found to be driven by the activation of the Kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor erythroid 2-related factor 2 (NRF2)/antioxidant response element (ARE) antioxidant pathway, through the generation of reactive oxygen species (ROS)

NAD+ IV therapy is not appropriate for everyone

Enhanced tolerance to photooxidative stress of transgenic Nicotiana tabacum with high chloroplastic glutathione reductase activity

Zinc cyclic di-AMP nanoparticles target and suppress tumours via endothelial STING activation and tumour-associated macrophage reinvigoration

The modulatory effect of GNS on intestinal homeostasis (Chao1, Shannon, and Simpson indices, PCoA, and F/B ratio) was demonstrated in an OVX mouse model of osteoporosis, which then restrained the metabolism of microbiota-related TMAO (betaine, choline, creatinine, carnitine, TMA, and TMAO) and the release of pro-inflammatory cytokines [TNF-, IL-6, and granulocyte colony-stimulating factor (G-CSF)], thereby inhibiting bone loss induced by estrogen deficiency