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Description
The tripeptide, glutathione, is one third glutamate and present at up to low millimolar intracellular concentrations in brain, mediating antioxidant defenses and drug detoxification

The Keap1-Nrf2 pathway plays a central role in the protection of cells against oxidative and xenobiotic stresses

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Changes in glutamatergic neuroplasticity has been proposed as one of the core mechanisms underlying the pathophysiology of depression