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One of the most prominent cytokines released by overexpressed cancer cells is Transforming growth factor-beta (TGF-), which occurs in both cancer cells and the surrounding microenvironment (Kuo et al

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Mutations at certain sites can change interface bond energy between monomers, disrupting NA stability and reducing the sensitivity of the virus to NAIs

[DOI] [PubMed] [Google Scholar] 79.Kodera Y., Suzuki A., Imada O., Kasuga S., Sumioka I., Kanezawa A., Taru N., Fujikawa M., Nagae S., Masamoto K., et al