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In 1981, for example, a paper published in the International Journal of Clinical Pharmacology, Therapy, and Toxicology described a trial with six volunteers who experienced immediate sleep pressure after intravenous DSIP infusion, as well as increased sleep time, decreased sleep onset, and better sleep efficiency without any sedative effects.13 Three years later, two other human trials across ten test subjects with insomnia found that DSIP administration yielded statistically significant improvements in several key sleep measures fewer sleep arousals, greater sleep efficiency, and increased REM, spindle, and slow-wave sleep.14 The above studies had shortcomings, namely their very small sample sizes, but the sleep-improving effects in cases of insomnia point to DSIPs potential to live up to its name

GHK-Cu suppressed the activation of p38 MAPK signaling pathway in LPS-induced RAW 264.7 cells activation A number of studies have demonstrated that the MAPK pathway plays important roles in lung inflammatory injury

But does it actually work

Pharmacologically, DSIP exhibits: Stress-Protective Effects : By mitigating stress-induced metabolic dysfunctions and oxidative damage ( 4, 8 )

[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Urso C, Caimi G

Scacheri et al., 2004), as well as addressing the issues of sequence-dependent and chemical-dependent toxicity ( in vitro and animal studies, there are no reports of such products being utilized in clinical trials thus far