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Description
It can be concluded that the dopaminergic deficit is efficiently compensated for a long period of time, at least 10 years or longer, during the normal or near-normal motor activity (silent/prodromal motor period) before clinical symptoms are sufficient for diagnosis (manifested period) [41]

Central nervous system (brain, retina, and spinal cord) neurodegenerative illnesses impact people of all ages (Figure 1)
10.1007/S12035-020-02227-3 38 SantomauroD

Mediators of inflammation 2016 , 8364279, (2016)

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