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When Trx1 and Trx2 are compromised, Grx2 expression is increased, and vice-versa

Physical therapy helped temporarily

Enzymes appear in italics

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Furthermore, investigating the relative degree of tumor dependency on exogenous glutamine at distinct stages of tumorigenesisthat is, in the primary tumor initiation and expansion, local tissue invasion, survival in the circulation and seeding, and colonization of distant organsmay provide further insights into the therapeutic potential of targeting glutamine metabolism in cancer therapy

10.1016/j.biortech.2005.03.028 Bioresource Technol