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The significant increase in LDH and CK-MB in the DOX-injured group confirms the induction of cardiotoxicity, consistent with previous studies showing DOX-induced cardiomyocyte necrosis and impaired membrane integrity 26,31,32

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This Insight explores why safety deserves a more central role, how firms can identify risk factors, and how they can unlock returns by including safety alongside typical PE priorities such as growth, performance, and exit readiness

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Both molecules are secreted matrix metalloproteases with disintegrin and thrombospondin motifs

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