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Increase in circulating products of lipid peroxidation (F 2 -isoprostanes) in smokers
But there are numerous situations under which changes in plasma halide/pseudohalide concentrations occur, resulting in an altered extent of HOCl formation by MPO
When activated, Nrf2 gets released from Keap1 and is translocated to nucleus
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Certain vitamins, for example, are light-sensitive, meaning the energy from light can change their chemical structure
doi: 10.1038/nature07310
