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A recent analysis of the USFDA Adverse Event Reporting System revealed that patients taking both metformin and a PPI experienced significantly higher rates of hospitalizations and life-threatening complications related to B12 deficiency (such as severe neuropathy and cognitive decline) compared to those on monotherapy

[7] [8] Whilst B12 deficiency can cause serious health problems, supplementation is generally well-tolerated by most individuals

excess is excreted

However, phentermine monotherapy remains indicated only for relatively brief use (several weeks up to 12 weeks) and is discontinued thereafter to mitigate tolerance and side effects

Careful observation is key to maintaining better control over your skin

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