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10.1038/s41418-022-00941-0 26 ChenJ.ZaalE

One of the first MAPK to draw attention in APAP hepatotoxicity is apoptosis signal-regulating kinase1 (ASK1), a mitogen-activated protein kinase kinase kinase (MAP3K), which regulates JNK and p38 pathways
Vitamin B1 (Thamaine) Thiamin plays a vital role in the growth and function of various cells
Lima is warm, Cusco is cool at night, and Puno is colder due to altitude

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These metabolites regulate intestinal barrier integrity, energy metabolism, and ovarian function by activating the AhR, modulating immune responses (e.g., IL-22), and influencing neuroendocrine pathways (e.g., 5-HT signaling (8587)