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As approximately 1221% of Caucasians are poor CYP2D6 metabolizers, compared to only 1% of Pacific islanders, this may explain the higher incidence of hepatotoxicity in Western countries [45]

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An assortment of epidemiological and clinical studies have stated glucose and lipid metabolism alterations, insulin resistance, and central obesity as predominant factors for the development of MetS [38, 212]

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An overview and management of osteoporosis

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