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Sarcomeric dysfunction in heart failure
Since scav-5 and scav-6 are paralogs of scav-4 , we analysed their functions in lipid accumulation using scav-5(ok1606) deletion mutants and scav-6 knockout alleles generated in this study through CRISPR/Cas9-mediated gene editing (Figure 4B)
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PDH converts pyruvate to acetyl-CoA, thus preventing lactate formation and tumor cell proliferation [90]
Subgroup analysis was not performed due to the low number of studies
