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One significant study evaluated oxidative stress status in both healthy cats and those diagnosed with HCM
Given that high serum IGF-1 and IGFBP5 expression correlate with elevated PD-L1 and poor post-ICB outcomes, these parameters may serve as biomarkers of immune exclusion and predictors of immunotherapy resistance in prostate cancer and potentially other malignancies
The function of IGFs in the MAPK signaling pathway provides a new direction in the fight against cancer
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