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Recently, a new long-lasting contraceptive composite hydrogel system has been able to achieve both physical blockage and chemical inhibition of sperm motility in the vas deferens by sequential injection of calcium alginate hydrogel, PEG-Au nanoparticles (PEG-AuNps), and ethylene diamine tetraacetic acid (EDTA) (Fig

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Protein S -nitrosylation, the covalent attachment of nitric oxide (NO) moiety to the reactive thiol group of a cysteine residue to form S -nitrosothiol is an important PTM for most classes of proteins (62)

doi: 10.1210/en.2006-0120

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