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They cannot be metabolized into active forms

Timing: Evening administration preferred

According to clinical research parenteral administration (intramuscular or intravenous) is preferred over other drug administration routes in case of emergency situations as it provides first-pass metabolism avoidance, reliable therapeutic concentrations and better bioavailability of dosage (2) It can also be used in situations when oral route is not feasible

Since 1mL = 100 units on a standard syringe, each 10 units (0.1mL) contains 250mcg

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This works for any concentration and any dose, which is why it is called universal