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Under harsh conditions such as elevated temperature, oxidative stress and nutrient deprivation, heat shock factors (HSFs) respond to proteotoxic stress by binding to heat shock elements (HSEs), thereby upregulating the expression of heat shock proteins (HSPs)

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4 phage clones (C7, B8, G12, G8) with the highest binding to SKOV3 and relatively low binding to HepG2 in cell-base ELISA were selected and further evaluated by flow cytometry

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