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Description
Researchers believe that this pain reduction occurs because that form of vitamin B12 strengthens nerve fibers, which are then not as susceptible to irritation by inflamed joints

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As indicated in Figure 2, oxidized GSH is recycled back to GSH by glutathione reductase (GR) with the consumption of nicotinamide adenine dinucleotide phosphate (NADPH)

This is a judgment call that depends on specific circumstances and how questions are phrased

doi: 10.1126/scitranslmed.3006585

7 and 8
