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Upon receptor binding, EPA and DHA form heterodimers with the retinoid X receptor (RXR) to activate peroxisome proliferator response elements (PPREs), enhancing fatty-acid oxidation and suppressing NF-B- and activator protein-1 (AP-1)-mediated cytokine transcription

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J Am Heart Assoc 5(5):e003046

Glutathione, initially described as philothion or love of sulfur was crystallized, determined to contain sulfur and renamed glutathione (125)

Collagen synthesis (in vitro): The tripeptide-copper complex stimulated fibroblast collagen synthesis at concentrations as low as 10^-9 M (PMID 3169264)

2F), and NADP(H)-dependent dehydrogenases typically exist in dimer forms