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Prescriptions for clomipramine hydrochloride capsules should be written for the smallest quantity of capsules consistent with good patient management, in order to reduce the risk of overdose

10.1161/jaha.117.006558 [DOI] [PMC free article] [PubMed] [Google Scholar] Blekkenhorst L

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Orally delivered NAC undergoes extensive first-pass metabolism resulting in about 90% loss by enzymatic deacetylation to form cysteine in the small intestine [9]