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[DOI] [PubMed] [Google Scholar] 157.Leone S., Chiavaroli A., Orlando G., Mollica A., Di Nisio C., Brunetti L., Vacca M

Topical resorcinol: Resorcinol is a chemical peeling agent with keratolytic and anti-inflammatory properties

Sporn MB, Dunlop NM, Newton DL, Smith JM

This, in turn, changes the characteristics of nerve fibers, which affects their ability to be stimulated and transmit signals

Importantly, oxidative stress markedly increases mucus cross-linking, making mucus more viscous and difficult to clear [77] and may account for the widespread mucus plugging seen in some patients with severe COPD [78]

The main roles for PGEs and PGI 2 in inflammation may in fact be in the generation of hyperalgesia, sensitization of the tissue to the irritant and pain producing activity of the amine and peptide type of mediators of inflammation (Ferreira and Nakamura, 1979
