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In the absence of critical cofactors synthesis of the master antioxidant glutathione from Hcy cannot proceed
The rate-limiting step in the de novo synthesis of the GSH is catalyzed by gamma-glutamyl-cysteine synthetase (also known as glutamine-cysteine ligase), which is a target gene of Nrf2
The lead variant is indicated, and the correlation of the LD effect relative to the lead variant is represented by the color scale
Vitamin D Vitamin D is vital for regulating immune function, which can directly impact thyroid health
