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Furthermore, miR-1307 was found to be a reliable predictor of chemotherapy effectiveness in patients, providing valuable guidance for individualized treatment plans in clinical settings

Besides their role in inflammation, these cytokines are detrimental to the processes of fertilization and embryo development: TNF- increases the free implants adhesions and their invasiveness through its effect on matrix metallo-proteinases (157) while TGF- hinders the local immune activity by inhibiting the natural killer cells which in turn impede the development of embryos (158)

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doi: 10.3389/fcell.2025.1622544 Received 03 May 2025 Accepted 11 June 2025 Published 30 June 2025 Volume 13 - 2025 Edited by Yangchun Xie, Second Xiangya Hospital, Central South University, China Reviewed by Matija Zelic, Sanofi Research and Development, United States Nik T