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Additionally, choline contributes to the production of lipid mediators such as lysophosphatidylcholine (lysoPC), sphingomyelin, and platelet-activating factor (28)

Randomized controlled trial of L-carnitine as a nutritional supplement in preterm infants

However, there is still theoretical concern that an antagonist at the N -methyl-d-aspartate receptor might affect fetal brain growth

de ah que parece conveniente en el futuro la realizacin de estudios multicntricos

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For patients not responding adequately at 12 weeks on a stable maintenance dose, clinicians should verify proper administration technique, assess adherence patterns, and consider whether further dose escalation is appropriate and tolerable before concluding the medication is ineffective