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Aizawa et al

"Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease"

Increased hydrostatic pressure drives fluid extravasation, manifesting as peripheral edema and hepatic congestion

In OC, peritoneal metastasis, elevated LPA in peritoneal fluid supports cell shedding, anoikis resistance, and collagen Imediated adhesion, driving peritoneal invasion via MEK/ERK and Akt signaling

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