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Frontiers in Systems Neuroscience

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152,153 In an animal study, the polyphenol resveratrol protected against toxin-induced tinnitus

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(2005) Recombinant, nonglycosylated human insulin-like growth factor-binding protein-3 (IGFBP-3) is degraded preferentially after administration to type II diabetics, resulting in increased endogenous glycosylated IGFBP-3

Exogenous administration of synthetic Ec peptides leads to phosphorylation of extracellular signal regulated kinases (ERK1 and ERK2), serine/threonine-specific protein kinase (Akt), IGF-1 and insulin receptor-independent cell growth [16] and produces mitogenic effect on human cell lines [17,18]