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(114, 115), and they need to be taken into account when designing a trial

The protocol begins at 2.5mg per week for four weeks, then escalates based on tolerability and response

Could it be that B12 was feeding budding tumors or something

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In the smoking cessation trial of Prado and colleagues, there was a significant reduction in depression [134], a secondary outcome also seen in the post- traumatic stress disorder trial of Kalivas and colleagues [99]

If you're currently on psychiatric medication antidepressants, anxiolytics, mood stabilizers don't adjust your treatment plan based on B12 results without involving your prescriber