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Under normal conditions, there is a well-regulated equilibrium in the GI mucosa between inflammatory cytokines (such as TNF-, IL-1, IL-6, IL-8, IL-17, and IL-23) and anti-inflammatory cytokines (like IL-5, IL-10, IL-11, and TGF-) (75)

However, other studies found that the inactive forms were effective

Additionally, xenograft tumor data showed that Gln significantly promoted tumor growth in vivo (Fig

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Concurrently, SMF significantly alters the composition of gut microbiota, particularly increasing the proportion of Akkermansia muciniphila [157]