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Description
GIP adds metabolic improvements through pancreatic and fat tissue effects

Other GLP-1R, GIPR, and glucagon receptor (GCGR) poly-agonists are in development and have been tested in phase 1 and phase 2 clinical trials, including GLP-1R/GCGR agonists, GLP-1R/GLP-2R agonists, and triple GLP-1R/GIPR/GCGR agonists (abstracts presented at the American Diabetes Association Annual Meeting in June, 2022 and (7))
Polyarginine peptides show high levels of cellular internalization and have high therapeutic potential

Ren S, Wang F, Shen J, Sun Y, Xu W, Lu J, et al

The free peptide chelates a Cu ion with high affinity, generating a deep cobalt-blue complex that is the workhorse molecule of modern copper-peptide research

Cell pellets were resuspended in 1 mL TRI reagent (Sigma)
