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For instance, although MMP-1 efficiently degrades collagen, it is predominantly expressed in AECs during IPF, where it promotes epithelial repair and inhibits apoptosiseffects suppressed by the dominant profibrotic mediator TGF- (Sang, 1998

(4) vehicle/vehicle group: rats were given vehicle (isotonic saline, 1 ml/kg per day, i.p.) 5 min before water administration (5 ml/kg per day by oral gavage)

Zsuzsanna Helyes et al

Pincus, Z., Mazer, T

They facilitate the conjugation of GSH with electrophilic compounds, aiding in the elimination of harmful substances

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