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Necessity was more frequent in patients with larger parenchymal and intraventricular blood volumes, imaging signs of hydrocephalus, midline shift, and cerebellar ICH (each P 2cm, presenting within 72 hours of onset with, or at risk of cerebral oedema with or without mass effect (limited GCS score = 4

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Importantly, this effector function is central to the anti-tumor activity of many IgG1-based therapies [198]

They achieve this by forming micelles that trap contaminants, allowing them to be rinsed away with water

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