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There's no risk of overdoseexcess B12 is simply excreted

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Discussion Significance of the study To our knowledge, this is the most comprehensive network meta-analysis comparing the efficacy of SL, IM, and oral routes of administration of vitamin B12 in patients with vitamin B12 deficiency

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and effectively reduces interstitial fibrosis and inflammatory cell infiltration in a UUO-induced renal fibrosis mice model