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Protective effects of puerarin on metabolic diseases: emphasis on the therapeutical effects and the underlying molecular mechanisms

Think of tyrosinase like a gatekeeper in a pigment workshop

Autoregulatory control of mitochondrial glutathione homeostasis

3000 x g , 4 C, 10 min), and concentrated 100-fold by ultrafiltration (Amicon, 100 kDa)

These metabolites also trigger immune responses by interacting with proteome arrays recognized by IgG antibodies, resulting in elevated antibody levels against protein adducts, correlating with ALD severity ( 3.2 Oxidative stress and its role in ALD Reactive oxygen species (ROS) are crucial regulators of cell signaling and stress responses (Nagy et al., 2016)

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