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It also seems unlikely that were on the cusp of a windfall of high-quality studies testing the safety and efficacy of peptides

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Unlike other ROS, it directly attacks biomolecules, causing extensive cellular damage through processes such as lipid peroxidation and DNA strand breaks [28, 29]

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Drug Metab Rev 44(1):88106, doi:10.3109/03602532.2011.602688 Jirillo E, Caccavo D, Magrone T, Piccigallo E, Amati L, Lembo A, Kalis C, Gumenscheimer M (2002) The role of the liver in the response to LPS: experimental and clinical findings

Overall, these studies suggest that fisetin exerts antitumor effects in ovarian cancer, including induction of apoptosis and necroptosis, inhibition of anti-apoptotic proteins, and reversal of chemotherapy resistance (Figure 6 and Table 1)
