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Description
This system is comprised of three different pathways

However, under oxidative stress, the depletion of GSH and accumulation of GSSG can compromise these functions, triggering apoptotic pathways and contributing to cell death [29,84]

doi: 10.1080/14656566.2020.1812578 157 PaulAKumarMDasPGuhaNRudrapalMZamanMK

& Toyokuni, S
Also, further expression of CCS, which is a copper chaperone assisting the maturation of SOD1 in vivo [21, 22], remarkably extends the survival of the transgenic mice administered with Cu II (atsm) [23]
(2) Animals with ALD
