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In the pioneering work by Oberley and Buettner published more than four decades ago, these authors suggested for the first time the importance of suppressed SOD2 (Mn-SOD) expression in cancer (Oberley and Buettner 1979)

This structural similarity allows them to merge with cellular membranes, facilitating the delivery of their contents directly into the cells

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674 In a TBI mouse model, HBED treatment can reduce microglia proliferation and aquaporin 4 expression, thereby alleviating secondary injury in the cortical region after TBI and improving motor function in mice