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this molecule directly influences testicular sperm maturation via stimulating glucose uptake by Sertoli cells

PARP1 and PARP2 Negatively Regulate SIRT1 Activity Poly ADP-ribose polymerase (PARP) is a ribozyme that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair which consumes molecular NAD +

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Nat Genet 1996;14:3615

The link between DNA damage and autophagy in thyroid cancer cells during ferroptosis has not yet been explored, and future mechanistic studies are needed to understand the exact relationship between the autophagy and DNA damage

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