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doi: 10.1093/brain/awae029 10 CompstonA.ColesA

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In addition to its role in feeding, evidence suggests that activation of MC3R may aid in insulin sensitivity and glucose control

1 Introduction Berberine (C 20 H 18 NO 4 , IUPAC name: 16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo [11.8.0.0 2,10 .0 4,8 .0 15,20 ] henicosa-1(13),2,4(8),9,14,16,18,20-octaene, PubChem CID: 2353), an isoquinoline quaternary alkaloid, isolated from different medicinal plants with a molar weight of 336.36 g/mol, including Hydrastis canadensis , Xanthorhiza simplicissima , Berberis aristata , Coptis chinensis , Coptis japonica , etc

in 2018 reported low expression of IFN- and IFN- in the macrophages of airway epithelium and subepithelium in asthmatic patients