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Dosage:10 mg/kg (Female STZ-diabetic), 30 mg/kg ( db/db mice, male control) Administration:p.o., daily, 16 weeks (Female STZ-diabetic), 26 weeks ( db/db mice, male control) Result:Significantly protected long-term memory and attenuated reductions in the volume of the CA1 and DG regions in type 1 diabetic mice

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When the molar ratio of the coordinating functional groups remains constant, the absorbance observed at 584 nm for the dimer was larger than that of the monomer peptide, indicating that D-P possesses better coordination efficacy and greater stability than M-P (Fig

vigorous shaking denatures the protein structure through mechanical stress

It demonstrated that the lipolytic activity of GH localizes to the C-terminal part and that a synthetic fragment can reproduce this activity without the other GH effects