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Antitumor activity of 2-meOE 2 [3] is thought to be mediated by antiproliferative and antimetastatic effects

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This phase delay is consistent with the delay induced by application of glutamate to SCN slices, suggesting that copper chelation may increase NMDAR activity, consistent with studies demonstrating copper-induced inhibition of NMDAR currents (Trombley & Shepherd, 1996

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