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Interestingly, viral ICP34.5 can block autophagy by several pathways, one of them is the inhibition of BECN1-mediated autophagy

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GH binding to GHR results in activation of JAK2, which subsequently phosphorylates multiple tyrosine residues on the ICD of the receptor (Figure 2) (6, 7)

Globotriaosylsphingosine induces oxidative DNA damage in cultured kidney cells

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