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In contrast, when other amino acids are deficient (at levels still sufficient to stimulate cell proliferation), cystine deprivation can effectively induce ferroptosis for anticancer therapy [42]

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doi: 10.1155/2019/5681701 2 GrazianiAScafaRGrandeGFerlinA

This change affects insulin secretion from the pancreas and the uptake and metabolism of glucose in organs such as the liver and muscles through the neuroendocrine pathway, ultimately influencing blood glucose and insulin levels (Ladyman and Grattan, 2017)

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doi:10.1002/ajmg.1320320235