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Xu, C., Akakuru, O
Those contexts are severe: acetaminophen overdose, septic shock, chronic obstructive pulmonary disease exacerbations

[DOI] [PubMed] [Google Scholar] 55.Kato S., Kato M., Abe Y., Matsumura T., Nishino T., Aoki M., Itoyama Y., Asayama K., Awaya A., Hirano A., et al
Luteolin can reduce inflammation in lung tissue by inhibiting NF-B translocation and pro-inflammatory cytokine release, making it a viable treatment for chronic lung problems [230]
For this reason, small molecule inhibitors to these kinases have been developed to target super enhancer regulatory elements and the proto-oncogenes under their transcriptional control
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