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Its converted into succinic acid via a B12-dependent enzyme

Glutamate dyshomeostasis in the CNS represents another critical target in MeHg-induced neurotoxicity (for a review, see Aschner et al., 2007)

HMGB1 regulates ferroptosis through Nrf2 pathway in mesangial cells in response to high glucose

4.1 NLRP3 inflammasome activation NLRP3 inflammasome is the most studied inflammasome comprised of NLRP3, an apoptosis associated speck-like protein containing a CARD (ASC) and procaspase ( via the internal interaction of the NACHT and LRRs domain

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KYN, kynurenine
