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Redox proteomic analysis of brain samples demonstrated that increased OS affects the final degradative process of autophagy, which relies on the activity of the vacuolar [H + ]-ATPase (V 0 -ATPase) and cathepsin D, both oxidized in AD individuals and in DS persons at risk of developing AD (233, 298, 342, 357)

Peer review Peer review information Nature thanks the anonymous reviewers for their contribution to the peer review of this work

[DOI] [PubMed] [Google Scholar] 13.Sirmans SM, Pate KA

Hypoglycemia with insulin or insulin secretagogues

5.6 Curcumin and ASD Curcumin (from Curcuma longa L (Zingiberaceae), rhizome